Two-component methods (TCSs), which encompass a histidine kinase (HK) sensor and a response regulator (RR), are vital for micro organism to rapidly sense and reply to varied environmental indicators. HKs and RRs sometimes perform as a cognate pair, interacting solely with each other to transduce signaling. Exact sign transduction in a TCS is determined by the particular interactions between the receiver area (RD) of the RR and the dimerization and histidine phosphorylation area (DHp) of the HK. Right here, we decided the advanced construction of KdpDE, a TCS consisting of the HK KdpD and the RR KdpE, which is accountable for Okay+ homeostasis.
Each the RD and the DNA binding area (DBD) of KdpE interacted with KdpD. Though the RD of KdpE and the DHp of KdpD contributed to binding specificity, the DBD mediated a definite interplay with the catalytic ATP-binding (CA) area of KdpD that was indispensable for KdpDE-mediated sign transduction. Furthermore, the DBD-CA interface largely overlapped with that of the DBD-DNA advanced, resulting in competitors between KdpD and its goal promoter in a KdpE phosphorylation-dependent method. As well as, the prolonged C-terminal tail of the CA area was crucial for stabilizing the interplay with KdpDE and for sign transduction.
Collectively, these information present a molecular foundation for particular KdpD and KdpE interactions that play key roles in environment friendly sign transduction and transcriptional regulation by this TCS. Gonadotropin-releasing hormone (GnRH) neurons within the hypothalamus coordinate fertility and puberty. So as to obtain profitable reproductive capability, they obtain indicators from the periphery and from different hypothalamic neurons that coordinate vitality homeostasis. Hormones, resembling estradiol, insulin, leptin, and adiponectin, act immediately or not directly on GnRH and its related reproductive neurons. Vitamins like glucose and fatty acids may have an effect on reproductive neurons to sign nutrient availability.
Moreover, acute and continual irritation is reported to detrimentally have an effect on GnRH and kisspeptin expression. All of those cues activate sign transduction pathways inside neurons that result in the modifications in GnRH neuronal perform. The signalling pathways may also be dysregulated by endocrine disrupting chemical substances, which impair fertility by misappropriating frequent signalling pathways. The advanced mechanisms controlling the degrees of GnRH through the reproductive cycle depend on a rigorously orchestrated set of sign transduction occasions to manage the constructive and adverse suggestions arms of the hypothalamic-pituitary-gonadal axis.
Built-in transcriptomic and metabolomic analyses reveal the results of callose deposition and multihormone sign transduction pathways on the tea plant-Colletotrichum camelliae interplay
Colletotrichum infects various hosts, together with tea vegetation, and might result in crop failure. Quite a few research have reported that organic processes are concerned within the resistance of tea vegetation to Colletotrichum spp. Nevertheless, the molecular and biochemical responses within the host throughout this interplay are unclear. Cuttings of the tea cultivar Longjing 43 (LJ43) had been inoculated with a conidial suspension of Colletotrichum camelliae, and water-sprayed cuttings had been used as controls.
In whole, 10,592 differentially expressed genes (DEGs) had been recognized from the transcriptomic information of the tea vegetation and had been considerably enriched in callose deposition and the biosynthesis of assorted phytohormones. If these signalling occasions are dysregulated, this can result’s a downregulatory occasion resulting in hypogonadal hypogonadism with decreased or absent fertility. Subsequently, an understanding of the mechanisms concerned in distinct neuronal signalling might present a bonus to tell therapeutic interventions for infertility and reproductive problems.
Subsequently, 3,555 mass spectra peaks had been obtained by LC-MS detection within the adverse ion mode, and 27, 18 and 81 differentially expressed metabolites (DEMs) had been recognized within the tea leaves at 12 hpi, 24 hpi and 72 hpi, respectively. The metabolomic evaluation additionally revealed that the degrees of the precursors and intermediate merchandise of jasmonic acid (JA) and indole-3-acetate (IAA) biosynthesis had been considerably elevated through the interplay, particularly when the signs grew to become obvious. In conclusion, we advise that callose deposition and numerous phytohormone signaling methods play vital roles within the tea plant-C. camelliae interplay.

Pores and skin photo-protection with phytochemicals in opposition to photo-oxidative stress, photo-carcinogenesis, sign transduction pathways and extracellular matrix remodeling-An outline
Extreme publicity of pores and skin to UV radiation triggers the era of oxidative stress, irritation, immunosuppression, apoptosis, matrix-metalloproteases manufacturing, and DNA mutations resulting in the onset of picture ageing and photo-carcinogenesis. On the molecular stage, these modifications happen by way of activation of a number of protein kinases in addition to transcription pathways, formation of reactive oxygen species, and launch of cytokines, interleukins and prostaglandins collectively. Present therapies accessible available on the market solely present restricted options and exhibit a number of negative effects.
The current paper gives perception into scientific research which have elucidated the constructive function of phytochemicals in counteracting the UV-induced depletion of antioxidant enzymes, elevated lipid peroxidation, irritation, DNA mutations, elevated senescence, dysfunctional apoptosis and immune suppression. The contribution of phytochemicals to the downregulation of expression of oxidative-stress delicate transcription components (Nrf2, NF-Kb, AP-1 and p53) and protein kinases concerned in irritation, apoptosis, immune suppression, extracellular matrix remodelling, senescence, picture ageing and photo-carcinogenesis, can also be mentioned.
Rat Extracellular Signal Regulated Kinase 1 (ERK1) ELISA Kit |
RD-ERK1-Ra-96Tests |
Reddot Biotech |
96 Tests |
EUR 723 |
Human Extracellular Signal Regulated Kinase 1 (ERK1) ELISA Kit |
DLR-ERK1-Hu-48T |
DL Develop |
48T |
EUR 498 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Extracellular Signal Regulated Kinase 1 (ERK1) in samples from tissue homogenates or other biological fluids. |
Human Extracellular Signal Regulated Kinase 1 (ERK1) ELISA Kit |
DLR-ERK1-Hu-96T |
DL Develop |
96T |
EUR 647 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Extracellular Signal Regulated Kinase 1 (ERK1) in samples from tissue homogenates or other biological fluids. |
Rat Extracellular Signal Regulated Kinase 1 (ERK1) ELISA Kit |
DLR-ERK1-Ra-48T |
DL Develop |
48T |
EUR 517 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Rat Extracellular Signal Regulated Kinase 1 (ERK1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Rat Extracellular Signal Regulated Kinase 1 (ERK1) ELISA Kit |
DLR-ERK1-Ra-96T |
DL Develop |
96T |
EUR 673 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Rat Extracellular Signal Regulated Kinase 1 (ERK1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Human Extracellular Signal Regulated Kinase 1 (ERK1) ELISA Kit |
RDR-ERK1-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 522 |
Human Extracellular Signal Regulated Kinase 1 (ERK1) ELISA Kit |
RDR-ERK1-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 724 |
Rat Extracellular Signal Regulated Kinase 1 (ERK1) ELISA Kit |
RDR-ERK1-Ra-48Tests |
Reddot Biotech |
48 Tests |
EUR 544 |
Rat Extracellular Signal Regulated Kinase 1 (ERK1) ELISA Kit |
RDR-ERK1-Ra-96Tests |
Reddot Biotech |
96 Tests |
EUR 756 |
Anti-ERK1 Rabbit Monoclonal Antibody |
M00104 |
BosterBio |
100ug/vial |
EUR 397 |
Description: Rabbit Monoclonal ERK1 Antibody. Validated in IP, IF, IHC, WB and tested in Human, Mouse. |
Anti-ERK1 Rabbit Monoclonal Antibody |
M00104-2 |
BosterBio |
100ug/vial |
EUR 397 |
Description: Rabbit Monoclonal ERK1 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat. |
Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody (Human) |
4-CAB357Hu22 |
Cloud-Clone |
-
EUR 251.00
-
EUR 2576.00
-
EUR 640.00
-
EUR 316.00
-
EUR 215.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Extracellular Signal Regulated Kinase 1 (ERK1) |
Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody (Human) |
4-MAB357Hu22 |
Cloud-Clone |
-
EUR 247.00
-
EUR 2516.00
-
EUR 626.00
-
EUR 310.00
-
EUR 214.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Extracellular Signal Regulated Kinase 1 (ERK1) |
Anti-ERK1/2 Rabbit Monoclonal Antibody |
M00104-1 |
BosterBio |
100ug/vial |
EUR 397 |
Description: Rabbit Monoclonal ERK1/2 Antibody. Validated in Flow Cytometry, IP, IF, ICC, WB and tested in Human, Mouse, Rat. |
Mouse signal transduction-Smad1 ELISA Kit |
CN-02562M1 |
ChemNorm |
96T |
EUR 480 |
Mouse signal transduction-Smad1 ELISA Kit |
CN-02562M2 |
ChemNorm |
48T |
EUR 331 |
Human signal transduction-Smad1 ELISA Kit |
CN-03384H1 |
ChemNorm |
96T |
EUR 448 |
Human signal transduction-Smad1 ELISA Kit |
CN-03384H2 |
ChemNorm |
48T |
EUR 297 |
Human signal transduction-Smad7 ELISA Kit |
CN-03385H1 |
ChemNorm |
96T |
EUR 448 |
Human signal transduction-Smad7 ELISA Kit |
CN-03385H2 |
ChemNorm |
48T |
EUR 297 |
Rat signal transduction-Smad1 ELISA Kit |
CN-01425R1 |
ChemNorm |
96T |
EUR 439 |
Rat signal transduction-Smad1 ELISA Kit |
CN-01425R2 |
ChemNorm |
48T |
EUR 290 |
Rat signal transduction-Smad7 ELISA Kit |
CN-01426R1 |
ChemNorm |
96T |
EUR 442 |
Rat signal transduction-Smad7 ELISA Kit |
CN-01426R2 |
ChemNorm |
48T |
EUR 293 |
Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody (Human), APC |
4-CAB357Hu22-APC |
Cloud-Clone |
-
EUR 351.00
-
EUR 3365.00
-
EUR 935.00
-
EUR 449.00
-
EUR 222.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Extracellular Signal Regulated Kinase 1 (ERK1). This antibody is labeled with APC. |
Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody (Human), Biotinylated |
4-CAB357Hu22-Biotin |
Cloud-Clone |
-
EUR 316.00
-
EUR 2526.00
-
EUR 744.00
-
EUR 387.00
-
EUR 221.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Extracellular Signal Regulated Kinase 1 (ERK1). This antibody is labeled with Biotin. |
Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody (Human), Cy3 |
4-CAB357Hu22-Cy3 |
Cloud-Clone |
-
EUR 427.00
-
EUR 4445.00
-
EUR 1205.00
-
EUR 557.00
-
EUR 254.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Extracellular Signal Regulated Kinase 1 (ERK1). This antibody is labeled with Cy3. |
Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody (Human), FITC |
4-CAB357Hu22-FITC |
Cloud-Clone |
-
EUR 301.00
-
EUR 2712.00
-
EUR 768.00
-
EUR 379.00
-
EUR 197.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Extracellular Signal Regulated Kinase 1 (ERK1). This antibody is labeled with FITC. |
Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody (Human), HRP |
4-CAB357Hu22-HRP |
Cloud-Clone |
-
EUR 321.00
-
EUR 2933.00
-
EUR 827.00
-
EUR 405.00
-
EUR 209.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Extracellular Signal Regulated Kinase 1 (ERK1). This antibody is labeled with HRP. |
Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody (Human), PE |
4-CAB357Hu22-PE |
Cloud-Clone |
-
EUR 301.00
-
EUR 2712.00
-
EUR 768.00
-
EUR 379.00
-
EUR 197.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Extracellular Signal Regulated Kinase 1 (ERK1). This antibody is labeled with PE. |
Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody (Human), APC |
4-MAB357Hu22-APC |
Cloud-Clone |
-
EUR 346.00
-
EUR 3284.00
-
EUR 914.00
-
EUR 440.00
-
EUR 219.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Extracellular Signal Regulated Kinase 1 (ERK1). This antibody is labeled with APC. |
Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody (Human), Biotinylated |
4-MAB357Hu22-Biotin |
Cloud-Clone |
-
EUR 312.00
-
EUR 2466.00
-
EUR 729.00
-
EUR 381.00
-
EUR 219.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Extracellular Signal Regulated Kinase 1 (ERK1). This antibody is labeled with Biotin. |
Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody (Human), Cy3 |
4-MAB357Hu22-Cy3 |
Cloud-Clone |
-
EUR 420.00
-
EUR 4337.00
-
EUR 1178.00
-
EUR 546.00
-
EUR 251.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Extracellular Signal Regulated Kinase 1 (ERK1). This antibody is labeled with Cy3. |
Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody (Human), FITC |
4-MAB357Hu22-FITC |
Cloud-Clone |
-
EUR 297.00
-
EUR 2647.00
-
EUR 751.00
-
EUR 372.00
-
EUR 195.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Extracellular Signal Regulated Kinase 1 (ERK1). This antibody is labeled with FITC. |
Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody (Human), HRP |
4-MAB357Hu22-HRP |
Cloud-Clone |
-
EUR 316.00
-
EUR 2862.00
-
EUR 809.00
-
EUR 398.00
-
EUR 207.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Extracellular Signal Regulated Kinase 1 (ERK1). This antibody is labeled with HRP. |
Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody (Human), PE |
4-MAB357Hu22-PE |
Cloud-Clone |
-
EUR 297.00
-
EUR 2647.00
-
EUR 751.00
-
EUR 372.00
-
EUR 195.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Extracellular Signal Regulated Kinase 1 (ERK1). This antibody is labeled with PE. |
ERK1 (5E9) Monoclonal Antibody |
EM1323-100ul |
ELK Biotech |
100ul |
EUR 279 |
Description: A Mouse Monoclonal antibody against ERK1 (5E9) from Human/ Rat/ Mouse. This antibody is tested and validated for IHC |
ERK1 (5E9) Monoclonal Antibody |
EM1323-50ul |
ELK Biotech |
50ul |
EUR 207 |
Description: A Mouse Monoclonal antibody against ERK1 (5E9) from Human/ Rat/ Mouse. This antibody is tested and validated for IHC |
Monoclonal Erk1/2 Antibody |
AMM04347G |
Leading Biology |
0.1ml |
EUR 484 |
Description: A Monoclonal antibody against Human Erk1/2. The antibodies are raised in Mouse. This antibody is applicable in WB |
Rabbit Polyclonal antibody Anti-CRBN |
Anti-CRBN |
ImmunoStep |
50 µg |
EUR 349 |
Anti-ERK1 antibody |
STJ97780 |
St John's Laboratory |
200 µl |
EUR 197 |
Description: ERK1 is a protein encoded by the MAPK1 gene which is approximately 41,3 kDa. ERK1 is localised to the cytoplasm, cytoskeleton ad nucleus. It is involved in RET signalling, activated TLR4 signalling, the IL-2 pathway, regulation of lipid metabolism and insulin signalling-generic cascades. This protein falls under the MAP kinase family and acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. Upon its activation, it translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. ERK1 is expressed in the cells of the nervous system, blood, lung, liver and skin. Mutations in the MAPK1 gene may result in small intestine neuroendocrine neoplasm. STJ97780 was developed from clone 5E9 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of MAPK3. |
Anti-ERK1 antibody |
STJ97781 |
St John's Laboratory |
200 µl |
EUR 197 |
Description: Mouse monoclonal to ERK1. |
Anti-ERK1 antibody |
STJ97782 |
St John's Laboratory |
200 µl |
EUR 197 |
Description: Mouse monoclonal to ERK1. |
Anti-ERK1 antibody |
STJ98942 |
St John's Laboratory |
200 µl |
EUR 197 |
Description: Rabbit polyclonal to ERK1. |
Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody (Human), APC-Cy7 |
4-CAB357Hu22-APC-Cy7 |
Cloud-Clone |
-
EUR 583.00
-
EUR 6610.00
-
EUR 1750.00
-
EUR 778.00
-
EUR 324.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Extracellular Signal Regulated Kinase 1 (ERK1). This antibody is labeled with APC-Cy7. |
Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody (Human), APC-Cy7 |
4-MAB357Hu22-APC-Cy7 |
Cloud-Clone |
-
EUR 572.00
-
EUR 6448.00
-
EUR 1709.00
-
EUR 761.00
-
EUR 319.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Mouse monoclonal antibody against Human Extracellular Signal Regulated Kinase 1 (ERK1). This antibody is labeled with APC-Cy7. |
Extracellular Signal Regulated Kinase 1 (ERK1) Antibody |
20-abx104964 |
Abbexa |
-
EUR 300.00
-
EUR 133.00
-
EUR 787.00
-
EUR 411.00
-
EUR 258.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Extracellular Signal Regulated Kinase 1 (ERK1) Antibody |
20-abx132233 |
Abbexa |
-
EUR 328.00
-
EUR 829.00
-
EUR 439.00
-
EUR 154.00
-
EUR 258.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Extracellular Signal Regulated Kinase 1 (ERK1) Antibody |
20-abx132252 |
Abbexa |
-
EUR 356.00
-
EUR 133.00
-
EUR 1024.00
-
EUR 509.00
-
EUR 300.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Extracellular Signal Regulated Kinase 1 (ERK1) Antibody |
20-abx007464 |
Abbexa |
-
EUR 300.00
-
EUR 439.00
-
EUR 189.00
|
|
|
Extracellular Signal Regulated Kinase 1 (ERK1) Antibody |
20-abx176350 |
Abbexa |
|
|
|
Extracellular Signal Regulated Kinase 1 (ERK1) Antibody |
20-abx172316 |
Abbexa |
|
|
|
Extracellular Signal Regulated Kinase 1 (ERK1) Antibody |
20-abx172317 |
Abbexa |
|
|
|
anti-Erk1 |
LF-PA0169 |
Abfrontier |
100 ul |
EUR 334 |
Description: Rabbit polyclonal to Erk1 |
anti-ERK1 |
YF-PA14008 |
Abfrontier |
100 ug |
EUR 403 |
Description: Rabbit polyclonal to ERK1 |
ERK1/2 (1H4) Monoclonal Antibody |
EM1326-100ul |
ELK Biotech |
100ul |
EUR 279 |
Description: A Mouse Monoclonal antibody against ERK1/2 (1H4) from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC |
ERK1/2 (1H4) Monoclonal Antibody |
EM1326-50ul |
ELK Biotech |
50ul |
EUR 207 |
Description: A Mouse Monoclonal antibody against ERK1/2 (1H4) from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC |
ERK1 Mouse Monoclonal Antibody (5E9) |
ABM40328-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
Description: A monoclonal antibody for detection of ERK1 from Human, Mouse, Rat. This ERK1 antibody is for IHC-P, IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen recombinant protein of ERK1 of MAPK3 |
ERK1 Mouse Monoclonal Antibody (5E9) |
ABM40328-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
Description: A monoclonal antibody for detection of ERK1 from Human, Mouse, Rat. This ERK1 antibody is for IHC-P, IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen recombinant protein of ERK1 of MAPK3 |
ERK1 Mouse Monoclonal Antibody (5E9) |
ABM40328-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
Description: A monoclonal antibody for detection of ERK1 from Human, Mouse, Rat. This ERK1 antibody is for IHC-P, IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen recombinant protein of ERK1 of MAPK3 |
ERK1 Mouse Monoclonal Antibody (1C11) |
ABM40329-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
Description: A monoclonal antibody for detection of ERK1 from Human, Mouse, Rat. This ERK1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen recombinant protein of ERK1 of MAPK3 |
ERK1 Mouse Monoclonal Antibody (1C11) |
ABM40329-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
Description: A monoclonal antibody for detection of ERK1 from Human, Mouse, Rat. This ERK1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen recombinant protein of ERK1 of MAPK3 |
ERK1 Mouse Monoclonal Antibody (1C11) |
ABM40329-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
Description: A monoclonal antibody for detection of ERK1 from Human, Mouse, Rat. This ERK1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen recombinant protein of ERK1 of MAPK3 |
ERK1 Mouse Monoclonal Antibody (4G11) |
ABM40330-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
Description: A monoclonal antibody for detection of ERK1 from Human, Mouse, Rat. This ERK1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen recombinant protein of ERK1 of MAPK3 |
ERK1 Mouse Monoclonal Antibody (4G11) |
ABM40330-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
Description: A monoclonal antibody for detection of ERK1 from Human, Mouse, Rat. This ERK1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen recombinant protein of ERK1 of MAPK3 |
ERK1 Mouse Monoclonal Antibody (4G11) |
ABM40330-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
Description: A monoclonal antibody for detection of ERK1 from Human, Mouse, Rat. This ERK1 antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen recombinant protein of ERK1 of MAPK3 |
ERK1 Mouse Monoclonal Antibody(5E9) |
44201-100ul |
SAB |
100ul |
EUR 252 |
ERK1 Mouse Monoclonal Antibody(1C11) |
44202-100ul |
SAB |
100ul |
EUR 252 |
ERK1 Mouse Monoclonal Antibody(4G11) |
44203-100ul |
SAB |
100ul |
EUR 252 |
ERK1/2 recombinant monoclonal antibody |
A5029 |
Bimake |
100ul X 3 |
EUR 595 |
|
Description: A recombinant monoclonal antibody from rabbit against human ERK1/2 for WB,ELISA |
Anti-ERK1/MAPK3 Antibody |
PA1343 |
BosterBio |
100ug/vial |
EUR 334 |
Anti-ERK1/2 antibody |
STJ97783 |
St John's Laboratory |
200 µl |
EUR 197 |
Description: Mouse monoclonal to ERK1/2. |
anti- ERK1/2 antibody |
FNab02844 |
FN Test |
100µg |
EUR 548.75 |
|
Description: Antibody raised against ERK1/2 |
anti- ERK1/2 antibody |
FNab02845 |
FN Test |
100µg |
EUR 505.25 |
|
Description: Antibody raised against ERK1/2 |
anti- ERK1/2 antibody |
FNab02846 |
FN Test |
100µg |
EUR 548.75 |
|
Description: Antibody raised against ERK1/2 |
anti- ERK1/2 antibody |
FNab02847 |
FN Test |
100µg |
EUR 585 |
|
Description: Antibody raised against ERK1/2 |
Extracellular Signal Regulated Kinase 1 (ERK1) Antibody (FITC) |
20-abx274649 |
Abbexa |
-
EUR 495.00
-
EUR 258.00
-
EUR 1455.00
-
EUR 676.00
-
EUR 398.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Human Signal transduction protein CBL- C, CBLC ELISA KIT |
ELI-50273h |
Lifescience Market |
96 Tests |
EUR 824 |
Mouse Signal transduction protein CBL- C, Cblc ELISA KIT |
ELI-33118m |
Lifescience Market |
96 Tests |
EUR 865 |
Recombinant Extracellular Signal Regulated Kinase 1 (ERK1) |
4-RPB357Hu01 |
Cloud-Clone |
-
EUR 494.24
-
EUR 235.00
-
EUR 1578.40
-
EUR 592.80
-
EUR 1085.60
-
EUR 394.00
-
EUR 3796.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Human Extracellular Signal Regulated Kinase 1 expressed in: E.coli |
anti-Erk1 (33A5) |
LF-MA0215 |
Abfrontier |
100 ul |
EUR 334 |
Description: Mouse monoclonal to Erk1 |
anti-Erk1 (9E6) |
LF-MA0389 |
Abfrontier |
100 ul |
EUR 334 |
Description: Mouse monoclonal Erk1 |
anti-ERk1 (11A9) |
LF-MA0390 |
Abfrontier |
100 ul |
EUR 334 |
Description: Mouse monoclonal Erk1 |
Anti-ERK1 (3C9) |
YF-MA10727 |
Abfrontier |
100 ug |
EUR 363 |
Description: Mouse monoclonal to ERK1 |
Anti-ERK1 (1B1) |
YF-MA14898 |
Abfrontier |
100 ug |
EUR 363 |
Description: Mouse monoclonal to ERK1 |
Anti-ERK1 (1E2) |
YF-MA14899 |
Abfrontier |
100 ug |
EUR 363 |
Description: Mouse monoclonal to ERK1 |
Anti-ERK1 (1F7) |
YF-MA14900 |
Abfrontier |
100 ug |
EUR 363 |
Description: Mouse monoclonal to ERK1 |
Anti-ERK1 (3D6) |
YF-MA14901 |
Abfrontier |
100 ug |
EUR 363 |
Description: Mouse monoclonal to ERK1 |
Conclusively, a number of phytochemicals maintain potential for the event of a viable resolution in opposition to UV irradiation-mediated picture ageing, photo-carcinogenesis and associated manifestations. Melanoma is a malignant pores and skin tumor, and its incidence is rising. To discover the particular variations in benign and malignant melanoma on the genetic stage, we carried out a sequence of bioinformatics analyses, together with differential gene evaluation, co-expression evaluation, enrichment evaluation, and regulatory prediction.