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Antibodies for signal transduction

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An experimental strategy to probe Gq contribution to signal transduction in living cells

June 22, 2021 by Aubree Russell
An experimental strategy to probe Gq contribution to signal transduction in living cells

Heterotrimeric G protein subunits Gαq and Gα11 are inhibited by two cyclic depsipeptides, FR900359 (FR) and YM-254890 (YM), each of that are getting used broadly to implicate Gq/11 proteins within the regulation of various organic processes. An rising main analysis query due to this fact is whether or not the mobile results of each inhibitors are on-target, i.e. mediated through particular inhibition of Gq/11 proteins, or off-target, i.e. the results of nonspecific interactions with different proteins. Right here we introduce a flexible experimental technique to discriminate between these potentialities. We developed a Gαq variant with preserved catalytic exercise, however refractory to FR/YM inhibition. A minimal of two amino acid adjustments have been required and ample to realize full inhibitor resistance. We characterised the

novel mutant in HEK293 cells depleted by CRISPR-Cas9 of endogenous Gαq and Gα11 to make sure exact management over the Gα-dependent mobile signaling route. Utilizing a battery of mobile outcomes with identified and hid Gq contribution, we discovered that FR/YM particularly inhibited mobile alerts following Gαq introduction through transient transfection. Conversely, each inhibitors have been inert throughout all assays in cells expressing the drug-resistant variant. These findings remove the chance that inhibition of non-Gq proteins contributes to the mobile results of the 2 depsipeptides.

We conclude that mixed software of FR or YM together with the drug-resistant Gαq variant is a strong in vitro technique to discern on-target Gq in opposition to off-target non-Gq motion. Consequently, it ought to be of excessive worth for uncovering Gq enter to advanced organic processes with excessive accuracy and the requisite specificity. Signaling between cells can promote each the event and development of most cancers. It has been discovered that chemical and bodily alerts, along with extracellular components, can affect most cancers development.

On this evaluate, we concentrate on the bodily microenvironment of most cancers cells and look at the motion of mechanical, electromagnetic, thermal, and acoustic alerts on most cancers cells, which can present new instructions for most cancers analysis and therapy. Thus, according to a lack of NMDAR operate, cocaine-induced ERK phosphorylation is attenuated. As a result of early NMDAR exercise contributes to the initiation of lasting addiction-relevant neuroadaptations, these information might maintain clues into mobile mechanisms liable for the event of cocaine habit.

Carbon dioxide-dependent sign transduction in mammalian programs

Carbon dioxide (CO2) is a elementary physiological gasoline identified to profoundly affect the behaviour and well being of hundreds of thousands of species inside the plant and animal kingdoms particularly. A latest Royal Society assembly on the subject of ‘Carbon dioxide detection in organic programs’ was extraordinarily revealing when it comes to the multitude of roles that completely different ranges of CO2 play in influencing crops and animals alike. Whereas excellent analysis has been carried out by main researchers within the space of plant biology, neuronal sensing, cell signalling, gasoline transport, irritation, lung operate and medical drugs, there’s nonetheless a lot to be realized about CO2-dependent sensing and signalling.

Notably, whereas a number of key sign transduction pathways and nodes of exercise have been recognized in crops and animals respectively, the exact wiring and sensitivity of those pathways to CO2 stays to be totally elucidated. On this article, we’ll give an summary of the literature referring to CO2-dependent sign transduction in mammalian programs. We’ll spotlight the primary sign transduction hubs by which CO2-dependent signalling is elicited with a view to raised understanding the advanced physiological response to CO2 in mammalian programs.

The principle subjects of dialogue on this article relate to how adjustments in CO2 affect mobile operate by modulation of sign transduction networks influenced by pH, mitochondrial operate, adenylate cyclase, calcium, transcriptional regulators, the adenosine monophosphate-activated protein kinase pathway and direct CO2-dependent protein modifications. Whereas every of those subjects might be mentioned independently, there’s proof of serious cross-talk between these sign transduction pathways as they reply to adjustments in CO2. In contemplating these core hubs of CO2-dependent sign transduction, we hope to delineate widespread components and establish areas wherein future analysis could possibly be greatest directed.

An experimental strategy to probe Gq contribution to signal transduction in living cells

Cocaine-Induced Synaptic Redistribution of NMDARs in Striatal Neurons Alters NMDAR-Dependent Sign Transduction

he consequence of repeated cocaine publicity and extended abstinence on glutamate receptor expression within the nucleus accumbens has been extensively studied. Nevertheless, the early results of cocaine on NMDAR signaling stay unknown. NMDAR signaling is dependent upon the subunit composition, subcellular localization, and the interplay with proteins on the postsynaptic density (PSD), the place NMDARs and different proteins type supercomplexes which might be liable for the signaling pathways activated by NMDAR-induced Ca2+ inflow. Right here, we investigated the impact of cocaine on NMDAR

Human signal transduction-Smad1 ELISA Kit

CN-03384H1 ChemNorm 96T
EUR 448

Human signal transduction-Smad1 ELISA Kit

CN-03384H2 ChemNorm 48T
EUR 297

Rat signal transduction-Smad1 ELISA Kit

CN-01425R1 ChemNorm 96T
EUR 439

Rat signal transduction-Smad1 ELISA Kit

CN-01425R2 ChemNorm 48T
EUR 290

Human signal transduction-Smad7 ELISA Kit

CN-03385H1 ChemNorm 96T
EUR 448

Human signal transduction-Smad7 ELISA Kit

CN-03385H2 ChemNorm 48T
EUR 297

Rat signal transduction-Smad7 ELISA Kit

CN-01426R1 ChemNorm 96T
EUR 442

Rat signal transduction-Smad7 ELISA Kit

CN-01426R2 ChemNorm 48T
EUR 293

Human Signal Transduction Primer Library

HSTL-I Real Time Primers 1 set
EUR 450

Human Signal transduction protein CBL- C, CBLC ELISA KIT

ELI-50273h Lifescience Market 96 Tests
EUR 824

Mouse Signal transduction protein CBL- C, Cblc ELISA KIT

ELI-33118m Lifescience Market 96 Tests
EUR 865

Human Mothers Against Decapentaplegic Homolog 1 (Smad1) ELISA Kit

RD-Smad1-Hu-48Tests Reddot Biotech 48 Tests
EUR 478

Human Mothers Against Decapentaplegic Homolog 1 (Smad1) ELISA Kit

RD-Smad1-Hu-96Tests Reddot Biotech 96 Tests
EUR 662

Rat Mothers Against Decapentaplegic Homolog 1 (Smad1) ELISA Kit

RD-Smad1-Ra-48Tests Reddot Biotech 48 Tests
EUR 511

Rat Mothers Against Decapentaplegic Homolog 1 (Smad1) ELISA Kit

RD-Smad1-Ra-96Tests Reddot Biotech 96 Tests
EUR 709

Human Mothers Against Decapentaplegic Homolog 1 (Smad1) ELISA Kit

DLR-Smad1-Hu-48T DL Develop 48T
EUR 479
Description: A sandwich quantitative ELISA assay kit for detection of Human Mothers Against Decapentaplegic Homolog 1 (Smad1) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Mothers Against Decapentaplegic Homolog 1 (Smad1) ELISA Kit

DLR-Smad1-Hu-96T DL Develop 96T
EUR 621
Description: A sandwich quantitative ELISA assay kit for detection of Human Mothers Against Decapentaplegic Homolog 1 (Smad1) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Mothers Against Decapentaplegic Homolog 1 (Smad1) ELISA Kit

DLR-Smad1-Ra-48T DL Develop 48T
EUR 508
Description: A sandwich quantitative ELISA assay kit for detection of Rat Mothers Against Decapentaplegic Homolog 1 (Smad1) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Mothers Against Decapentaplegic Homolog 1 (Smad1) ELISA Kit

DLR-Smad1-Ra-96T DL Develop 96T
EUR 661
Description: A sandwich quantitative ELISA assay kit for detection of Rat Mothers Against Decapentaplegic Homolog 1 (Smad1) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Mothers Against Decapentaplegic Homolog 1 (Smad1) ELISA Kit

RDR-Smad1-Hu-48Tests Reddot Biotech 48 Tests
EUR 500

Human Mothers Against Decapentaplegic Homolog 1 (Smad1) ELISA Kit

RDR-Smad1-Hu-96Tests Reddot Biotech 96 Tests
EUR 692

Rat Mothers Against Decapentaplegic Homolog 1 (Smad1) ELISA Kit

RDR-Smad1-Ra-48Tests Reddot Biotech 48 Tests
EUR 534

Rat Mothers Against Decapentaplegic Homolog 1 (Smad1) ELISA Kit

RDR-Smad1-Ra-96Tests Reddot Biotech 96 Tests
EUR 742

Anti-ERK1 (E32) Signal Transduction Monoclonal Antibody

ABP-MAB-ES001 Allele Biotech 100 ug Ask for price

Anti-ERK1 (E19) Signal Transduction Monoclonal Antibody

ABP-MAB-ES002 Allele Biotech 100 ug Ask for price

Smad1/ Rat Smad1 ELISA Kit

ELA-E0647r Lifescience Market 96 Tests
EUR 886

Smad1/ Rat Smad1 ELISA Kit

ELI-02285r Lifescience Market 96 Tests
EUR 886

Anti-ERK1/2 (E31R) Signal Transduction Monoclonal Antibody

ABP-MAB-ES003 Allele Biotech 100 ug Ask for price

QuantiSir Specific Gene Knockdown Quantification Kit For Signal Transduction - ViDR

P-5008 EpiGentek 96 Assays
EUR 788.05
Description: Ask the seller for details

Bacillus subtilis Signal transduction histidine-protein kinase/phosphatase DegS (degS)

1-CSB-EP320275BRJ Cusabio
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Bacillus subtilis Signal transduction histidine-protein kinase/phosphatase DegS(degS) expressed in E.coli

Custom Antibody titration by ELISA up to 2 rabbits and 1 bleed

ELISA-1 Alpha Diagnostics 1
EUR 202

Sheep Smad1 ELISA Kit

ESS0276 Abclonal 96Tests
EUR 521

Rat Smad1 ELISA Kit

ERS0276 Abclonal 96Tests
EUR 521

Rabbit Smad1 ELISA Kit

ERTS0276 Abclonal 96Tests
EUR 521

Monkey Smad1 ELISA Kit

EMKS0276 Abclonal 96Tests
EUR 521

Mouse Smad1 ELISA Kit

EMS0276 Abclonal 96Tests
EUR 521

Porcine Smad1 ELISA Kit

EPS0276 Abclonal 96Tests
EUR 521

Goat Smad1 ELISA Kit

EGTS0276 Abclonal 96Tests
EUR 521

Bovine Smad1 ELISA Kit

EBS0276 Abclonal 96Tests
EUR 521

Chicken Smad1 ELISA Kit

ECKS0276 Abclonal 96Tests
EUR 521

Canine Smad1 ELISA Kit

ECS0276 Abclonal 96Tests
EUR 521

Anserini Smad1 ELISA Kit

EAS0276 Abclonal 96Tests
EUR 521

Smad1 Cell ELISA Kit

abx595549-96tests Abbexa 96 tests
EUR 637

Human SMAD1 ELISA Kit

ELA-E0647h Lifescience Market 96 Tests
EUR 824

Bovine SMAD1 ELISA KIT

ELI-02283b Lifescience Market 96 Tests
EUR 928

SMAD1

GT15219 Neuromics 100 ug
EUR 526

Guinea Pig Smad1 ELISA Kit

EGS0276 Abclonal 96Tests
EUR 521

Smad1 DNA-Binding ELISA Kit

abx596539-96tests Abbexa 96 tests
EUR 723

SMAD1 ELISA Kit (Mouse) (OKCD06627)

OKCD06627 Aviva Systems Biology 96 Wells
EUR 1001
Description: Description of target: ;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 0.125ng/mL

SMAD1 ELISA Kit (Mouse) (OKEH05787)

OKEH05787 Aviva Systems Biology 96 Wells
EUR 662
Description: Description of target: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). May play a role in the initiation and maintenance of spermatogenesis. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 31.34 pg/mL

SMAD1 ELISA Kit (Rat) (OKEH07161)

OKEH07161 Aviva Systems Biology 96 Wells
EUR 662
Description: Description of target: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). Has been shown to be also activated by TGF-beta (transforming growth factor) type I receptor kinase in rat intestinal epithelial cells (IEC 4-1). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.159 ng/mL

SMAD1 ELISA Kit (Bovine) (OKEH07443)

OKEH07443 Aviva Systems Biology 96 Wells
EUR 1092
Description: Description of target: ;Species reactivity: Bovine;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 36pg/mL

SMAD1 ELISA Kit (Rabbit) (OKWB00419)

OKWB00419 Aviva Systems Biology 96 Wells
EUR 572
Description: Description of target: ;Species reactivity: Rabbit;Application: ;Assay info: Assay Type: Quantitative Sandwich ELISA;Sensitivity: 0.188 ng/mL

Smad1/MADH1 ELISA KIT|Human

EF000681 Lifescience Market 96 Tests
EUR 689

Recombinant KH Domain Containing, RNA Binding, Signal Transduction Associated Protein 1 (KHDRBS1)

4-RPL650Hu01 Cloud-Clone
  • EUR 499.62
  • EUR 236.00
  • EUR 1598.56
  • EUR 599.52
  • EUR 1099.04
  • EUR 397.00
  • EUR 3846.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human KH Domain Containing, RNA Binding, Signal Transduction Associated Protein 1 expressed in: E.coli

Recombinant KH Domain Containing, RNA Binding, Signal Transduction Associated Protein 1 (KHDRBS1)

4-RPL650Mu01 Cloud-Clone
  • EUR 510.37
  • EUR 239.00
  • EUR 1638.88
  • EUR 612.96
  • EUR 1125.92
  • EUR 404.00
  • EUR 3947.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse KH Domain Containing, RNA Binding, Signal Transduction Associated Protein 1 expressed in: E.coli

KH Domain Containing, RNA Binding, Signal Transduction Associated Protein 1 (KHDRBS1) Antibody

20-abx128380 Abbexa
  • EUR 453.00
  • EUR 133.00
  • EUR 1302.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 2 (KHDRBS2) Antibody

20-abx307678 Abbexa
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

KH Domain Containing, RNA Binding, Signal Transduction Associated Protein 1 (KHDRBS1) Antibody

20-abx104762 Abbexa
  • EUR 467.00
  • EUR 133.00
  • EUR 1344.00
  • EUR 634.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 2 (KHDRBS2) Antibody

abx034990-400ul Abbexa 400 ul
EUR 523

KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 2 (KHDRBS2) Antibody

abx034990-80l Abbexa 80 µl
EUR 286

KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 2 (KHDRBS2) Antibody

20-abx007227 Abbexa
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 2 (KHDRBS2) Antibody

abx224066-100ug Abbexa 100 ug
EUR 411

KH Domain Containing, RNA Binding, Signal Transduction Associated Protein 1 (KHDRBS1) Antibody

20-abx327286 Abbexa
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

ViraDuctin Retrovirus Transduction Kit (40 Transductions)

RV-200 Cell Biolabs 40 transductions
EUR 363
Description: The efficiency of retrovirus infection of target cells tends to be lower than that of adenovirus. Additives such as Polybrene® can increase transduction efficiencies, but even then only a small fraction of retroviral vectors can trasduce many target cell lines. Our ViraDuctin Retrovirus Transduction Kit provides superior transduction efficiencies in a variety of cell lines, even when compared to transductions in the presence of Polybrene®. This system is ideal for many primary cells as well as immobilized cells.

ViraDuctin Retrovirus Transduction Kit (200 Transductions)

RV-201 Cell Biolabs 200 transductions
EUR 780
Description: The efficiency of retrovirus infection of target cells tends to be lower than that of adenovirus. Additives such as Polybrene® can increase transduction efficiencies, but even then only a small fraction of retroviral vectors can trasduce many target cell lines. Our ViraDuctin Retrovirus Transduction Kit provides superior transduction efficiencies in a variety of cell lines, even when compared to transductions in the presence of Polybrene®. This system is ideal for many primary cells as well as immobilized cells.

ViraDuctin Lentivirus Transduction Kit (40 Transductions)

LTV-200 Cell Biolabs 40 transductions
EUR 345
Description: Lentiviral expression has many advantages over other viruses, including the ability to infect both proliferating and non-proliferating cells. The efficiency of lentivirus infection of target cells, however, tends to be lower. Additives such as Polybrene can increase transduction efficiencies, but even then only a small fraction of lentiviral vectors can trasduce many target cell lines. Our ViraDuctin Lentivirus Transduction Kit provides superior lentiviral transduction efficiencies in a variety of cell lines, even when compared to transductions in the presence of Polybrene. This system is ideal for many primary cells as well as immobilized cells.

ViraDuctin Lentivirus Transduction Kit (200 Transductions)

LTV-201 Cell Biolabs 200 transductions
EUR 751
Description: Lentiviral expression has many advantages over other viruses, including the ability to infect both proliferating and non-proliferating cells. The efficiency of lentivirus infection of target cells, however, tends to be lower. Additives such as Polybrene can increase transduction efficiencies, but even then only a small fraction of lentiviral vectors can trasduce many target cell lines. Our ViraDuctin Lentivirus Transduction Kit provides superior lentiviral transduction efficiencies in a variety of cell lines, even when compared to transductions in the presence of Polybrene. This system is ideal for many primary cells as well as immobilized cells.

ViraDuctin AAV Transduction Kit (10 Transductions)

AAV-200 Cell Biolabs 10 transductions
EUR 421
Description: The process by which adeno-associated virus (AAV) infects host cells includes viral binding and entry, intracellular trafficking, nuclear transport, and viral second strand DNA synthesis. The second strand DNA synthesis has been shown to be the rate limiting step, which leads to inefficient transduction by AAV vectors. ViraDuctin AAV Transduction Kit is a proprietary, multi-reagent formulation designed to increase the efficiency of transduction by AAV vectors. Reagent preparation takes only 10 minutes prior to host cell infection.

ViraDuctin AAV Transduction Kit (50 Transductions)

AAV-201 Cell Biolabs 50 transductions
EUR 972
Description: The process by which adeno-associated virus (AAV) infects host cells includes viral binding and entry, intracellular trafficking, nuclear transport, and viral second strand DNA synthesis. The second strand DNA synthesis has been shown to be the rate limiting step, which leads to inefficient transduction by AAV vectors. ViraDuctin AAV Transduction Kit is a proprietary, multi-reagent formulation designed to increase the efficiency of transduction by AAV vectors. Reagent preparation takes only 10 minutes prior to host cell infection.

ViraDuctin Adenovirus Transduction Kit (10 Transductions)

AD-200 Cell Biolabs 10 transductions
EUR 415
Description: Adenoviral infection of most cells is mediated largely by the coxsackievirus-adenovirus receptor (CAR). In many cells, however, this receptor is either absent or present at extremely low levels, reducing the efficiency of adenovirus uptake. ViraDuctin Adenovirus Transduction Reagent is designed specifically to increase the efficiency of adenoviral transduction without regard to the level of CAR expression on the surface of the target cells.

ViraDuctin Adenovirus Transduction Kit (50 Transductions)

AD-201 Cell Biolabs 50 transductions
EUR 949
Description: Adenoviral infection of most cells is mediated largely by the coxsackievirus-adenovirus receptor (CAR). In many cells, however, this receptor is either absent or present at extremely low levels, reducing the efficiency of adenovirus uptake. ViraDuctin Adenovirus Transduction Reagent is designed specifically to increase the efficiency of adenoviral transduction without regard to the level of CAR expression on the surface of the target cells.

Mouse KH Domain Containing, RNA Binding, Signal Transduction Associated Protein 1 (KHDRBS1) Protein

20-abx067639 Abbexa
  • EUR 718.00
  • EUR 286.00
  • EUR 2207.00
  • EUR 843.00
  • EUR 509.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human KH Domain Containing, RNA Binding, Signal Transduction Associated Protein 1 (KHDRBS1) Protein

20-abx166241 Abbexa
  • EUR 704.00
  • EUR 286.00
  • EUR 2151.00
  • EUR 829.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Smad1 Colorimetric Cell-Based ELISA Kit

EKC1526 BosterBio 100ul
EUR 572

Smad1 (pS187) DNA Binding ELISA Kit

abx596638-96tests Abbexa 96 tests
EUR 754

Smad1 / 5 / 9 Cell ELISA Kit

abx595866-96tests Abbexa 96 tests
EUR 637

Smad1 DNA-Binding ELISA Kit (OKAG00440)

OKAG00440 Aviva Systems Biology 96 Wells
EUR 753
Description: Description of target: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.;Species reactivity: Human, Mouse, Rat;Application: ELISA;Assay info: Assay Type: Qualitative DNA Binding ELISA ;Sensitivity:

SMAD1 Antibody

CSB-PA998747- Cusabio
EUR 335
Description: A polyclonal antibody against SMAD1. Recognizes SMAD1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

SMAD1 Antibody

CSB-PA998747-100ul Cusabio 100ul
EUR 316
Description: A polyclonal antibody against SMAD1. Recognizes SMAD1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

SMAD1 Antibody

CSB-PA825094- Cusabio
EUR 335
Description: A polyclonal antibody against SMAD1. Recognizes SMAD1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

SMAD1 Antibody

CSB-PA825094-100ul Cusabio 100ul
EUR 316
Description: A polyclonal antibody against SMAD1. Recognizes SMAD1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

SMAD1 Antibody

1-CSB-PA841004 Cusabio
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against SMAD1. Recognizes SMAD1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200

SMAD1 Antibody

1-CSB-PA009928 Cusabio
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against SMAD1. Recognizes SMAD1 from Human, Mouse, Rat, Monkey. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/5000

SMAD1 Antibody

1-CSB-PA004104 Cusabio
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against SMAD1. Recognizes SMAD1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/10000

SMAD1 Antibody

1-CSB-PA005538 Cusabio
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against SMAD1. Recognizes SMAD1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000

SMAD1 Antibody

1-CSB-PA042170 Cusabio
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against SMAD1. Recognizes SMAD1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100

SMAD1 Antibody

1-CSB-PA021786GA01HU Cusabio
  • EUR 597.00
  • EUR 333.00
  • 150ul
  • 50ul
Description: A polyclonal antibody against SMAD1. Recognizes SMAD1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB

SMAD1 Antibody

1-CSB-PA618998HA01HU Cusabio
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against SMAD1. Recognizes SMAD1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500

SMAD1 Antibody

1-CSB-PA618998LA01HU Cusabio
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against SMAD1. Recognizes SMAD1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:600, IF:1:50-1:200

SMAD1 Antibody

32160-100ul SAB 100ul
EUR 252

SMAD1 siRNA

20-abx934282 Abbexa
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

SMAD1 siRNA

20-abx934283 Abbexa
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

Smad1 Antibody

48784-100ul SAB 100ul
EUR 333

Smad1 Antibody

48784-50ul SAB 50ul
EUR 239

Smad1 Antibody

49149-100ul SAB 100ul
EUR 333

Smad1 Antibody

49149-50ul SAB 50ul
EUR 239

Smad1 Antibody

AF6451 Affbiotech 200ul
EUR 304
Description: Smad1 Antibody detects endogenous levels of total Smad1.
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subunit composition and subcellular localization after each intraperitoneal non-contingent cocaine and response-contingent intravenous cocaine self-administration in mice. We discovered that repeated cocaine publicity, whatever the route or contingency of drug administration, decreases NMDAR interactions with the PSD and synaptic lipid rafts within the accumbens shell and dorsal striatum. We offer proof that cocaine triggers an early redistribution of NMDARs from synaptic to extrasynaptic websites, and that this adaptation has implications within the activation of downstream signaling pathways.

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  • fusion
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  • high
  • Spoligotyping
  • Tumour prevention by a single antibody domain targeting the interaction of signal transduction proteins with RAS.

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